I came across this the other day while looking up Stephanie Meyers (Twilight series of novels) on Wikipedia: She did not think she could be a writer but she gave it a go. After she wrote her first novel Twilight, she sent out 15 queries; five went unanswered, nine brought rejections, and the last query was a positive response from Jodi Reamer of Writers House. The rest is history. She is listed on the Forbes list of the top 100 powerful celebrities, and she makes $50M a year. I just found it amazing how negative the response was to her queries in light of the success of her novel(s); if as a noob novelist (at that time) she had that level of negativity starting out, on even a blockbuster novel, why should noob wannabe novelists (myself included) expect any less response when sending out queries.