@Lemon flavoured, I like Michelle Rodriguez, but even her physique is far from what the character is. Physique-wise she could play Amélie who's into boxing, but anyone who played Lise would need to be built like e.g. a taller version of Minna Pajulahti, but I doubt there'll ever be an actress that muscular because standardized beauty ideals. If Gwendoline Christie bulked up, she could probably pull it off, especially since the character is 6' tall and Christie is 6'3, but by the time the film would go into production, I'm not sure if she could pass off as a 21yo anymore since she's 36 already. Maybe if she had a daughter, she might be of the right age by that time.
We don't have a big cast of characters and most would be CGI, but I personally pegged Katharine Isabelle as Discordia, because she does both crazy and apathy so, so well. In a perfect world, Anup/Anubis would be Idris Elba or Isaiah Mustafa. You're welcome.
Marckus: Doug Bradley Late 80s early 90s and for the rest I have no clue as to who would be a good fit with my characters. Also not sure if a live action, or CGI is the way to go. This is a neat idea though.
Jacob's Trials Jacob Denofa: Milo Ventimiglia Kevin White- Ed Norton Mike Johnson- Michael K. Williams Karen Denofa- Kate Bosworth Roz White- Anna Paquin Brian Pemberton- Ben Foster Fred Reynolds- Norman Redus Tony Uniewski- Justin Timberlake Jacob's alien father- William Hurt Matt Bell- Josh Harnett as a bearded stoner