Sometimes you need to preceed 'and' with a comma in a list. Depends on what you're trying to say. Also, if you have to reword a sentence to make it clear without an Oxford comma, it proves the point the pro-comma people are making.
Haha, LOL'd. As for the topic: I use it for two reasons: it seems clearer to me and it's also common in American English, so I see no reason to avoid it. It's never used in my mother-tongue, though, so it took for me a while to get used to it. Now lists look weird if I don't use it.
I use comma's as a tool, like semicolons, colons, and periods. There are rules and guidelines behind them, but at the end of the day, what works works. I probably have some punctuation in places that people wouldn't use it, and not in places where people would. But I use comma's, such as the Oxford comma, to dissect and set the tempo of my writing as necessary.
That difference in language can also cause issues, even if it's just between American English and UK English. It also depends what audience you are aiming for but what if you are aiming for a global audience? If the author is in the UK, but the story is set in the USA and you want people worldwide to read it, which way do you choose? Which way is the most popular?
Any reader who would refuse to read a work because of either the inclusion or exclusion of the Oxford comma is a reader I can do without.