Yeah certain personalities really aren't amenable to being gender flipped without losing their charm. There's a certain kind of cheeky, charming, larger than life guy who, on becoming a woman, would find themselves no longer being able to charm the girls in their office. Similarly there's a sort of woman who's a bit self-conscious and shy who's very relatable but who'd become a bit pathetic if male. Which is not to say you can't write characters like that and play off the fact that they aren't immediately what you'd expect but you have to write them to be that. You can't just gender flip them in a story and have them read the same way. As it turns out 'everyman' characters don't become 'everywoman'. It's more unique or heroic characters that are more amenable to flipping their gender because their unique qualities mark them out whatever gender they are. In my stories; no I don't think I could just flip the main character and have them work well. In contemporary teen romance I think you do need a female lead. Teenage boys just don't worry about the same things, or perhaps more accurately if they do the audience won't connect with it in the same way. In the book I'm writing right now there's an element of gender flipping going on. The protagonist is very tomboyish; she can be aggressive and even violent and can drink and shag and so forth. But she's still a girl under that and she needs to be for it to work. The contradiction in her is what makes her interesting. A boy being a bit gross and reveling in it would be really boring, just what we expect. For her though there's some duality to her, things pulling her in different directions. And of course no sixteen year old boy can just walk into a party and shag whoever he fancies no matter how much he might wish that was the case. But pretty much no teenage boy can resist a girl who'll say "Fancy a shag?" .
Ginzaekh-- now Ginazara-- ends up with Ash instead of Gazi. He confides with Gazi in everything like before, but now in a sisterly way instead of a romantic way, which means, instead of confiding in her as they grow closer romantically in the novel, they have always confided in each other since they became friends. Ginzaekh, bearing a girl name, is no longer named after his-- now her-- father. His personality and way of thinking would be different because different sexes' brains are inherently, biologically different. Life would be even harder for his family since the oldest male would be his little brother, so there is no "man of the house" as the saying goes, since the father is dead. Instead of taking up a trade, Ash would provide for the family with whatever trade he chose-- say, leatherworking. But as an adolescent providing for a fatherless family, Ginazara would still hunt. If the family she starts with Ash struggles financially, she might take up butchery like her mother. I don't know if the story would change all that much, really, but she might experience a bit of sexism when she fulfills roles traditionally held by males. The Riphalaron has never been female, for example, but if the Rishnaran chose Ginazara as he does Ginzaekh, Ginazara would be the first. Also, periods. Dragon periods are the worst. Almost as bad as the alternative, which ends with laying an egg, which is as painful as human childbirth but worse since the egg is proportionally larger in relation to the dragoness's birth canal (not that that's the correct term for a dragon, but I'm too tired to look it up right now.) And the egg is not as flexible as a baby. Imagine giving birth to a cantaloupe except the cantaloupe is a hard boiled egg and the surface of the egg is much firmer, barely squeezable. (Khrizan eggs harden and expand after being laid, but they aren't much softer before this happens. Only soft enough not to cause too much damage to the mother's body, and their bodies are designed to heal afterward, so the egg isn't afraid to wreak a little damage.) After that, the stretched-out cloaca is bandaged so it can constrict again (a cloaca that recently been used to give birth is the only area where Khrizans are concerned with modesty, and it's less sexual and more that it's just plain gross to look at the gaping orange hole. Yes, orange, they have orange blood and inner tissue.) So after the cloaca is bound, the scales that were scraped off from the inside of the cloaca by the laying process are swept up and disposed of, and you've eaten a bear's weight in medicinal berries, you are rewarded for your labor with having to sit on your handiwork for nine months until it cracks open, at which point you bond with your newborn child and then hand it straight over to the father so you can take a year off or so recovering from the stress, and when you're done you take over the child's nurture and decide it was all worth it and you might do it again someday. But the unpleasant part usually sinks in by the third kid and you realize you don't want to have any more and you're happy with the children you have. Once your kids have left the nest (not that Khrizans have lived in literal nests since they became evolved, intelligent beings) you just assume you're infertile because you sure as heckfire aren't going to go to the trouble of actually birthing kids again because you miss them. But hey, if you can adopt, you wouldn't mind-- although your grown-up kids might treat their new baby brother a little weird since he's younger than your grandchildren. On second thought, you have grandchildren, what do you need more kids for? Well, that turned into... something else. Good night!
If my MC was a female, then I guess he/she would be a fraternal twin. Also, it would ruin a sort of theme I'm trying to include, "It's okay for guys to be emotional."
Sexually liberated spinster in charge of an opium operation and combats eldritch forces. Tbh he's too androgynous personality-wise so the main change overall would be how external people treat him/her. However a big change would be his son who was born and raised by a mistress would've been in a very different circumstance growing up, a bastard son to a rich lady.
Gender-stereotypes-challenging sixteenth-century girl would become... a much more boring, conventional sixteenth-century man. I guess part of the fun/interest in writing tomboy girl characters in historical fiction is that they are already half gender-flipped and this causes interesting reactions in their society...