It ruins...ok not "ruins" but it creates an atmosphere where people mock it for "internet points"...but stymied several concepts.
Scream had its moments, but it ruined mass-market horror movies for a generation. Precisely for the reasons mentioned here: Scream's attempt at subverting horror cliches rapidly became a huge cliche as all the other movies copied it. Pretty much every movie for years after had to include some character saying 'hey, it's just like we're in a horror movie, wink, wink'. Fortunately that's harder to do in written fiction, because writing a book is much cheaper than making a movie. But I have found that many books have become very predictable because you just know they're going to follow the new cliche of never following the old cliche. And movies are even worse: if I never see another 90lb girl beating up six 200lb men at the same time, it'll be too soon.
I agree with that assessment of Scream. And yeah, when it comes to fiction I'd say I read something like 90% classics and 10% contemporary. With non-fiction it's practically the opposite.