I mean weird as in alien, something irreconcilable to any degree with our universe. The Edge Chronicles have this kind of setting, but even better examples are Tower of Babylon and Exhalation, by Ted Chiang. I also think that steampunk should count- Chiang has a story set in a Victorian-era Britain where alchemy works, Kabbalah functions as a science and the industrial revolution was driven by golems. Right now I'm trying to create a setting in which deities govern regions or aspects of nature like feudal fiefdoms, and one of my goals is to eliminate any point of reference with Earth. I don't want it to be set on a planet or in a recognizable universe, and I want the deities to act very differently from historical pagan gods (not to mention gods in well-known fantasy universes). The point is to present something genuinely fresh. Please post your advice/thoughts, or even better, a recounting of an actual attempt. I'd also love some other examples of this fiction, if anyone knows them.